Synthesis of Novel Quinazolinone-Benzothiazole Hybrid Com...
Abbot, Vikrant / Bhardwaj, Varun / Sharma, Poonam
Some new amino substituted quinazoline compounds were synthesized and evaluated for their anticancer activity at National Cancer Institute (NCI), U.S.A. Among the synthesized nine compounds, two were selected for single high dose screening (10-5 M) in full 60 cell panel. Among the selected compounds, 2-benzamido-N-(benzo[d]thiazol-2-yl)benzamide 4 exhibited significant anticancer activity against non-small cell lung cancer NCI-H23, colon cance...