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This book describes the biology, occurrence, and methods of control of the commonest congenital malformations of the nervous system: neural tube defects, spina bifida, encephalocoele, and anencephalus. It reviews the epidemiology of these conditions and discusses issues such as ascertainment, seasonal variation, ethical and legal issues.

Cancer control is the term applied to the development of integrated population-based approaches to reduce the incidence and mortality from cancer and to minimize its impact on affected individuals and on the community. The integrated nature of cancer control is reflected in this multi-disciplinary text, the first in this rapidly developing field.

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Significant progress has been made in recent years in understanding the origins of cutaneous maligant melanoma. Knowledge of the relationship between solar radiation and melanoma has changed and it now appears that both the character and timing of exposure may be more important than total cumulative dose in accounting for risk. The melanoma-sunlight model may prove an instructive heuristic exercise for environmental epidemiology, as we current...