The Pten Family
Eng, Charis (Genomic Medicine Institute Lerner Research Institute) / Ngeow, Joanne (National Cancer Centre Singapore) / Stambolic, Vuk (Princess Margaret Cancer Centre Uhn)
Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine covers all aspects of PTEN biology and its roles in human diseases. The contributors discuss the structural characteristics of PTEN, its functions at the plasma membrane as well as in the cytoplasm and nucleus, the mutations, interacting partners, and posttranslational modifications that affect its expression levels, subcellular localiz...