Mechanisms of Organ Dysfunction in Critical Illness
Fink, Mitchell P. / Evans, Timothy W.![Mechanisms of Organ Dysfunction in Critical Illness](https://support.digitalhusky.com/media/annotations/sorted/154/15437842/CHSBZCOP0315437842.jpg)
The pathophysiology of sepsis can be regarded as a series of steps, beginning with the invasion of normally sterile tissue by microbes and the elaboration of various pro-inflammatory mediators. The final common pathway is often the development of the multiple organ dysfunction syndrome (MODS). Whereas a great deal has been learned during the past quarter century about the inflammatory processes associated with sepsis (and other related conditi...