Leukemia and Lymphoma: Molecular and Therapeutic Insights
Kharas, Michael G / Levine, Ross L / Melnick, Ari M
Written and edited by experts in the field, this collection covers our current understanding of the molecular underpinnings of leukemia and lymphoma, as well as recent progress in development of therapies that target them. The contributors review the normal functions of hematopoietic stem cells--the precursors to white blood cells--and then examine the genetic, epigenetic, and cellular mechanisms that drive malignant transformation. The roles ...