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Addressing all aspects of brain death and thoroughly detailing how a potential organ donor should be maintained to ensure maximum use of the organs and cells, The Brain-Dead Organ Donor: Pathophysiology and Management is a landmark addition to the literature.  This first-of-its-kind, multidisciplinary volume will be of interest to a large section of the medical community. The first section of the book reviews the historical, medical, legal, an...

Acute endocranial hypertension leads to significant hemodynamic changes resulting from the release of endogenous and circulating catecholamines. This response induces the first set of injury affecting all organs used for transplantation. The rapid reduction of Free Triiodothyronine (T3), T4, cortisol, insulin and antidiuretic hormone leads to a second set of tissue injury, progressive inability to metabolize fuels aerobically and inability to ...