Evaluation of Aqueous Solubility of Hydroxamic Acids by P...
Pande, Rama / Patre, Sandhya / Thakur, Piyush Kumar
The aqueous solubility of drugs plays a key role in pharmaceutical, environmental and biological processes. It is an important factor in the ADMET (absorption, distribution, metabolism, elimination and toxicity) research. Since the experimental determination of water solubility is time-consuming therefore, reliable computational predictions are used for the pre-selection of acceptable drug like compounds. The Partial Least Squares (PLS) regres...