The general structure of the myosin filament has been known since the classical x-ray diffraction studies of Huxley and Brown (1963). However, one of the crucial features, namely, the filament ordering or the number of myosin cross-bridges per 143 Å repeat, has been controversial throughout (Squire, 1981). Analysis of myofibrillar proteins by means of one-dimensional sodium dodecyl sulfate polyacrylamide gels has yielded conflicting results. T...
CHF 32.90