Synthesis and Biological Evaluation of 6 fluoro 3 piperid...
S. P., Sharath Chandra![Synthesis and Biological Evaluation of 6 fluoro 3 piperidin 4 yl benzo d isoxazole derivatives for their Antipsychotic Properties](https://support.digitalhusky.com/media/annotations/sorted/441/44123178/CHSBZCOP0344123178.jpg)
Our present study focuses on synthesis, characterisation and antipsychotic evaluation of 6-fluoro-3-(piperidin-4-yl) benzo[d]isoxazole derivatives. A new series of benzisoxazole derivatives were synthesized, which are close structural analogs of risperidone, a known second generation antipsychotic drug. The structures of the newly synthesized molecules were confirmed by 1) NMR, LC MS, FTIR and elemental analysis. In silico analysis of the para...