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Vascular-Targeted Therapies in Oncology

Siemann, Dietmar W. (University of Florida Shands Cancer Center, USA)
Vascular-Targeted Therapies in Oncology
Attacking a tumor's supportive blood vessel network may offer novel means of improving cancer cure rates. The vasculature is critical to tumor development, survival, growth and metastatic spread. However, tumor blood vessels are abnormal, both morphologically and functionally, and display characteristics that distinguish them from normal vasculature. It is these inherent differences between blood vessels associated with tumors and those associ...

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