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This book presents selected papers from the 11th International Symposium on Heating, Ventilation and Air Conditioning (ISHVAC 2019), with a focus on HVAC techniques for improving indoor environment quality and the energy efficiency of heating and cooling systems. Presenting inspiration for implementing more efficient and safer HVAC systems, the book is a valuable resource for academic researchers, engineers in industry, and government regulators.

The ability to detect and quantify apoptosis, to understand its biochemistry, and to identify its regulatory genes and proteins is crucial to biomedical research. In Apoptosis: Methods and Protocols, Second Edition, expert researchers describe the techniques to best investigate the critical steps involved in the apoptotic process. Presented from several different research perspectives, the volume contains sections covering detection of apoptos...

Many of the genes found in the human major histocompatibility complex (MHC:HLA region) are subject to extreme polymorphism. HLA polymorphism has been used extensively in solid organ and bone marrow transplantation to match donors and recipients. Many MHC genes also have significant disease association and play a pivotal role in the control of immune response. In MHC Protocols, leading experts detail readily reproducible methods for identifying...

This second edition volume expands on the previous edition with a discussion of new and updated methods used to study the Herpes Simplex Virus (HSV), along with a look at the latest developing technologies such as next generation sequencing, CRISPR/Cas9 engineering, and the use of BioID to identify protein-protein interactions. Chapters cover topics such as the biology, life cycle, and current state of antiviral and vaccine development for HSV...

This book, now in a thoroughly revised second edition, offers a comprehensive review of the rapidly growing field of optogenetics, in which light-sensing proteins are genetically engineered into cells in order to acquire information on cellular physiology in optical form or to enable control of specific network in the brain upon activation by light. Light-sensing proteins of various living organisms are now available to be exogenously expresse...

Following an introductory overview, Hyperthermia In Cancer Treatment: A Primer comprehensively describes the biological reasons for associating hyperthermia with radiation and chemotherapy and the biological and clinical effects of hyperthermia on cancerous and normal tissues. The volume's 20 chapters are arranged in three principal parts: physical and methodological studies, biologic principles, and clinical studies.

Continuous regeneration of the cornea is necessary to maintain this tissue in the transparent state that is essential for vision. Therapy for repair of the damaged anterior cornea is currently addressed through the transplantation of donor corneas or the delivery of limbal epithelial stem cells (LESC) to the ocular surface using amniotic membrane (AM) as a supporting scaffold. Research on the bioengineering of corneal equivalents as replacemen...

Thoroughly revised and updated, Optimization in Drug Discovery: In Vitro Methods, Second Edition presents a wide spectrum of in vitro assays including formulation, plasma binding, absorption and permeability, cytochrome P450 (CYP) and UDP-glucuronosyltransferases (UGT) metabolism, CYP inhibition and induction, drug transporters, drug-drug interactions via assessment of reactive metabolites, genotoxicity, and chemical and photo-mutagenicity ass...

This book was compiled by researchers of Chinese Academy of Forestry, Sichuan Agricultural University, Chinese Academy of Sciences, Southwest Forestry University, and Kunming University of Science and Technology. It has been the most comprehensive monograph about the bamboo resources in China until now. "Illustrated Flora of Bambusoideae in China" is composed of two volumes.This volume 1 contains three sections. The first section includes pref...

This book discusses key concepts, challenges and potential solutions in connection with established and emerging topics in advanced computing, renewable energy and network communications. Gathering edited papers presented at MARC 2018 on July 19, 2018, it will help researchers pursue and promote advanced research in the fields of electrical engineering, communication, computing and manufacturing.

Affecting over a hundred million individuals worldwide, retinal diseases are among the leading causes of irreversible visual impairment and blindness, and appropriate study models, especially animal models, are essential to furthering our understanding of the etiology, pathology, and progression of these endemic diseases. In Animal Models for Retinal Diseases, recognized experts in the field highlight valuable techniques as well as animal mode...

With nearly one hundred years of intensive study, lipids have proven to be a vital and ever-more-promising area of cell biological research. In Liposomes: Methods and Protocols, leading experts in the related fields explore cutting-edge experimental methods involving all aspects of lipids as essential components of the cell membrane. Volume 1: Pharmaceutical Nanocarriers focuses on the state-of-the-art aspects of developing liposome-based nano...

Many fundamental discoveries concerning epigenetics and the elucidation of mechanisms of epigenetic regulation have developed from studies performed in plants. In Plant Epigenetics and Epigenomics: Methods and Protocols , leading scientists in the epigenetics field describe comprehensive techniques that have been developed to understand the plant epigenetic landscape.  These include recently developed methods and techniques for analysis of epi...

Studies over the past decade have continued to bring tremendous advances to our understanding of bone biology. New pathways have been discovered and expanded our knowledge of the ways in which genes and gene products affect bone cells and thereby bone mass and bone strength. In Bone Research Protocols, Second Edition, expert researchers in the field detail many methods commonly used to study bone biology. Focusing mainly on in vitro methods, t...

This book mainly focuses on Chinese science and technology in modern and contemporary China, as well as Western technology, especially modern European science, which greatly influenced Chinese society in the Qing dynasty. It also discusses the collision and integration of the East and West leading to modern China, addressing topics such as modern Chinese physics, mathematics, publication of scientific works and modern scientific education. Thi...

Ureteroscopy: Indications, Instrumentation¿& Technique provides a comprehensive and state-of-the-art review of ureteroscopy and will serve as a valuable resource for urologists throughout the world.¿ The volume provides evidence based outcomes to support the expanding indications for ureteroscopy as well as a strong emphasis on appropriate patient selection.¿ The book also provides detailed recommendations for the step-by-step approach to uret...

Epithelial mucins are large complex cell surface and secreted glycoproteins produced by mucosal epithelial cells.  In, Mucins: Methods and Protocols expert researchers in the field detail many of the methods which are now commonly used to study Mucins. These include methods and techniques  for the best approaches to analysing each specific area of mucin biochemistry, physiology and biophysics before providing individual detailed experimental p...

Biological warfare has, unfortunately, in the post 9/11 world become a significant topic of discussion in both the medical and lay presses. In the wake of the biological "letter bombs" containing anthrax spores, the possibility of biologic and/or toxic attacks on civilians in any part of the world became no longer a possibility. It is now part of common discussion and consciousness. This book presents the history of the topics and clinically r...

Continuing progress has been made in understanding the brain at the molecular, anatomic, and physiological levels in the years following the "Decade of the Brain, " with the results providing insight into the underlying basis of many neurological disease processes. In Neuroscience in Medicine,  Third Edition, a distinguished panel of basic and clinical investigators, noted for their teaching excellence, provide thoroughly updated and revised c...

The integration of endocrinology in critical care medicine has led to new experimental and clinical data on the complex endocrine and metabolic derangements accompanying non-endocrine severe illnesses. The joining of these two disciplines has generated important novel insights with significant clinical implications. Acute Endocrinology: From Cause to Consequence compiles these new findings into an important and highly relevant new resource. Pa...