Pharmacogenomic Effect on Biopharmaceutics of Anti-Tuberc...
Modgil, Swati / Thakur, Shivani / Rana, Rajat The first line anti-tuberculosis drugs are known to cause dose related adverse drug reactions like peripheral neuritis and hepatotoxicity. The risk of getting peripheral neuritis have been avoided through a concomitant administration of pyridoxine, while hepatotoxicity remains to be a major adverse effect of anti- tuberculosis therapy. Research findings state reduction in the incidence of hepatotoxicity by exploring a potential link between bi...