BACKGROUND:Chronic bacterial infection may be a causative agent that explains part of the link between childhood poverty and adult coronary heart disease. Hence, search for new risk factors in the development of unstable angina especially the infections like helicobacter pylori . Most of the studies showed either inconsistent association between unstable angina and Helicobacter pylori infection . Hence, we are justified in conducting a study to know the association between unstable angina and Helicobacter pylori infection. METHODS:30 patients admitted in Kasturba medical hospitals admitted with the history of unstable angina were evaluated for helicobacter pylori infection by the serological test of IgG H.Pylori by ELISA method. 30 age and sex matched controls were studied and evaluated by the similar method. RESULTS:Out of 30 cases, 15 were positive for IgG H.Pylori (50%) and out of 30 controls 14 were positive for H.Pylori (46.66%). The P value was found to be 0.79. Hence, it was not statistically significant. CONCLUSION:Based on our small study we found that there is no association between Unstable angina and Helicobacter pylori infection.