This issue of Child and Adolescent Psychiatric Clinics will provide a comprehensive review of Depression in Special Populations within child and adolescent psychiatry. Guest edited by Drs. Karen Wagner and Warren Ng, this issue will discuss a number of related topics that are important to practicing child psychiatrists. This issue is one of four selected each year by our series Consulting Editor, Dr. Todd Peters. Articles in this volume include, but are not limited to: Foster care/child welfare, Juvenile Justice, Deaf and Hard of Hearing, African American/Latino, HIV and Depression, Children of military families, Depression in American Indian Youth, Depression in Medically Ill Children, Youth Depression in School Settings, Sexual Minority Youth LGBTQ, Youth with Substance Use, Transitional Age Youth, and College Mental Health, among others.