1. Internet 2. Sequence Analysis 3. Calculation of Sequence Alignments for Evolutionary Inferences and to Aid in Structural and Functional Analysis 4.Computational Biology (Biological Database Management System) 5.Computational Biology (Information Retrieval from Databases 6. Phylogenetic Analysis 7. Phylogenetic Prediction 8. Genetic Engineering 9. DNA Sequencing 10. Genome Mapping 11. Gene Prediction / Identification