Frontmatter -- Preface -- Contents -- I. A HISTORICAL NOTE -- Two thousand years of fibrinogen research and evidence for fibrin being the first protein / Henschen, A. -- II. GENE ANALYSIS -- Fibrinogen evolution - The structure and evolution of fibrinogen: The coiled coil region / Fowlkes, D. M. / Mullis, N. T. / Comeau, C. M. / Crabtree, G. R. -- Absence of gross defect of fibrinogen genes in one patient with congenital afibrinogenemia / Courtois, G. / Uzan, G. / Assouline, Z. / Marguerie, G. / Kahn, A. -- III. FIBRINOGEN-FIBRIN CONVERSION -- Fibrinogen to fibrin - an overview / Blombäck, B. -- Fibrin - specific monoclonal antibodies are elicited by immunization with a synthetic fibrin-like peptide / Matsueda, G. R. / Hui, K. Y. / Haber, E. -- Enhancement of fibrin polymerization by active site - inhibited thrombin / Kaminski, M. / McDonagh, J. -- Peptides released from human fibrinogen by thrombic enzymes / Harenberg, J. / Vries, J. X. de / Waibel, S. -- The analysis of fibrinopeptide release from S--carboxymethylated fibrinogen chains using high-performance liquid chromatography / Southan, C. / Hensc, A. -- Moaification of the fibrin a-chain by dipeptidyl peptidase IV / Mentlein, R. / Struckhoff, G. / Heymann, E. -- IV. FIBRINOGEN-FIBRIN INTERACTION -- Analysis of composition of soluble fibrinogen/fibrin complexes by differential ultracentrifugation / Shainoff, J. R. -- Reversible interactions of fibrin and fibrinogen: an ultracentrifugation study / Preissner, K. T. / Rotker, J. / Selmayr, E. / Fasold, H. / Müller-Berghaus, G. -- V. NORMAL FIBRINOGEN VARIANTS -- Evidence that the amount of heparin precipitable fraction is influenced by fibrinogen quality / Holm, B. / Godal, H. C. -- The location of a second in vivo phosphorylation site in the Aa-chain of human fibrinogen / Seydewitz, H. H. / Kaiser, C. / Witt, I. -- Evidence that the y chain population of human platelet fibrinogen lacks the y' variant that is present in plasma fibrinogen / Mosesson, M. W. / Homandberg, G. A. / Amrani, H. L. -- Differences and similarities between human adult and fetal fibrinogen fragments D1 / Galanakis, D. K. -- VI. ABNORMAL FIBRINOGEN VARIANTS -- Functional defects in abnormal fibrinogens / Carrell, N. / McDonagh, J. -- Study of 10 cases of congenital dysfibrinogenemia: clinical and molecular biological aspects / Soria, J. / Soria, C. / Samama, M. / Caen, J. -- Fibrinogens Sydney I and II, a kinetic study of (His16 )FPA cleavage and its effect on FPB cleavage / Southan, C. / Henschen, A. / Lane, D. A. -- Fibrinogens London I - IV, Manchester, Sydney I and II. Cleavage of fibrinopeptides by thrombin and expression of their polymerisation abnormalities / Lane, D. A. / Ireland, H. / Thompson, E. / Southan, C. / Henschen, A. -- Aspects of evaluation of fibrinogen Stony Brook - A defect resulting in failure to release fibrinopeptide A / Galanakis, D. K. / Henschen, A. -- Fibrinogen Tokyo II: An abnormal fibrinogen with an impaired polymerization site on the aligned DD domain of fibrin molecules / Matsuda, M. / Nakamikawa, C. / Baba, M. / Morimoto, K. -- Fibrinogen Milan II: A congenital dysfibrinogenemia with a defective clotting by thrombin, normal clotting by arvin, reptilase and prothrombin-staphy1ocoagulase complex, associated with thrombotic episodes / Haverkate, F. / Koopman, J. / Kluft, C. / Mannucci, P. M. / d'Angelo, A. / Bertina, R. M. -- Preliminary report concerning two new cases of congenital dysfibrinogenemia (Homburg II and Homburg III) / Miyashita, C. / Schwamborn, J. / Blohn, G. von / Wenzel, E. / Hellstern, P. -- The effect of sodium citrate on fibrin polymerisation in patients with liver disease / Francis, J. L. / Watson, N. J. / Simmonds, V. J. / Armstrong, D. J. -- VII. FIBRINOGEN DEGRADATION PRODUCTS -- Studies of the proteolytic fragments of the C-terminal portion of the a-chain of human fibrinogen / Mihalyi, E. -- Biodistribution or human fibrinogen-derived peptides in rabbits / Harenberg, J. / Stehle, G. / Waibel, S. / Eisenhut, M. / Hermann, H. -J. -- Structure-function studies on a vasoactive pentapeptide derived from plasm in degradation of human fibrin(ogen) / Wallin, R. / Saldeen, K. / Saldeen, T. -- Purification and characteristics of a vasoactive peptide derived from elastase degradation of human fibrin(ogen) / Wallin, R. / Saldeen, K. / Belew, M. / Ohlsson, K. / Saldeen, T. -- Relation of crosslinked to non crosslinked fibrin derivatives in tumor ascites compared to cirrhosis ascites / Hafter, R. / Klaubert, W. / Gollwitzer, R. / Hugo, R. von / Graeff, H. -- VIII. INTERACTION WITH PLASMINOGEN AND ITS ACTIVATOR -- Study of the interaction between plasminogen and fibrinogen degradation products using immunoenzymological assay / Soria, J. / Soria, C. / Dunn, F. / Deguchi, K. / Mirshahi, M. / Lijnen, R. / Nieuwenhuizen, W. / Haverkate, F. / Samama, M. / Caen, J. -- Fibrin and plasminogen structures involved in the tissue-type plasminogen activator catalyzed activation of plasminogen / Verheijen, J. / Nieuwenhuizen, W. / Traas, D. / Chang, G. / Hoegee-de Nobel, B. -- Kinetics of the tissue-type plasminogen activatormediated activation of plasminogen. Influence of CNBr fibrin(ogen) fragment FCB-2 and different forms of plasminogen / Nieuwenhuizen, W. / Voskuilen, M. / Traas, D. W. / Hoegee-de Nobel, B. / Verheijen, J. H. -- IX. INTERACTION WITH CELLS -- Structural characterization of the recognition site for platelet receptors on human fibrinogen / Hawiger, J. / Kloczewiak, M. / Timmons, S. / Lukas, T. J. -- Binding or fibrinogen to ADP-treated platelets: Importance of the Aa-chain / Peerschke, E. I. B. / Galanakis, D. K. -- Inhibition of fibrinogen binding to activated platelets by oligoamines / Agam, G. / Luria, R. / Shoshani, L. / Livne, A. -- Specific interaction between fibrinogen-fibrin and endothelial cells / Dejana, E. / Languino, L. R. / Dauden, V. M. / Balconi, G. / Marguerie, G. -- Influence of fibrin, fibrinogen and fibrinogen degradation products on cultured endothelial cells / Tanaka, K. / Watanabe, K. -- Interaction of fibrin with malignant melanoma cells in long term culture / Jelenska, M. / Kopec, M. / Rochowska, M. / Skurzak, H. -- AUTHOR INDEX -- SUBJECT INDEX -- Backmatter