This book presents a new threat modelling approach that specifically targets the hardware supply chain, covering security risks throughout the lifecycle of an electronic system. The authors present a case study on a new type of security attack, which combines two forms of attack mechanisms from two different stages of the IC supply chain. More specifically, this attack targets the newly developed, light cipher (Ascon) and demonstrates how it can be broken easily, when its implementation is compromised with a hardware Trojan. This book also discusses emerging countermeasures, including anti-counterfeit design techniques for resources constrained devices and anomaly detection methods for embedded systems.