This issue of Emergency Medicine Clinics, edited by Drs. Stephen Borron and Ziad Kazzi focuses on emergencies arising from contact with Hazardous Materials. Article topics include: Selected classes and examples of dangerous industrial chemicals, weapons of mass destruction, and their syndromic identification, Hospital preparedness for chemical and radiological disasters, Personnel protection and decontamination of adults and children, Resources for toxicological information and assistance, Asphyxiants, Corrosives and irritants, Organophosphates and carbamates, Intentional and unintentional food, drug, and water contamination, and more!