The text opens with coverage of the basic concepts of molecular pathology, principles of genetics, and basic laboratory principles. The next chapters provide a review of inherited disorders, the molecular basis of cancer, and specific cancers both in solid tumors and in hematological malignancies. The final chapters cover specialized topics: pharmacogenetics, identity testing, and selected infectious organisms. All of this material has been completely revised and updated to reflect important advances in the field. The Second Edition also includes clinical case examples.
TOC:Basic Concepts in Molecular Pathology.- Genetic Inheritance.- Mutation.- Methods in Molecular Pathology.- Inherited Disorders.- Molecular Origins of Cancer.- Familial Cancer Syndromes.- Pharmacogenetics.- Identity Testing.- Infectious Diseases