A young wife and her husband inherit a house in the mountains of North Carolina. Locals believe a werewolf roams the valley, and they believe her husband was bitten by the werewolf while hiking in the forest and will become one himself. When the night of the full moon arrives, she is in dire peril. A Voodoo practitioner, Dr. Thibault, is creating an army of zombies. The Frankenstein monster falls into his hands and he revives it using Voodoo. A teenage couple working for the doctor, discover his activities, putting them in grave danger.