This issue of Dermatologic Clinics, guest edited by Dr. Seemal R. Desai of The University of Texas Southwestern Medical Center, is devoted to Therapeutic Hotline: New Developments in Dermatology. Articles in this timely issue address updates in psoriasis, hair loss, nail diseases, photoprotection, melanoma, pediatric dermatology, pigmentary disorders, women's skin health, acne, atopic dermatitis, bullous diseases, rosacea, and genetic skin diseases.