Development of new more potent drugs is requirement of present times. This Book "Topological Modeling and Drug Designing" deals with basics of QSAR, Graph theory, Topological modeling, Statistics used, designing of best models leading to drug discovery and development of new drugs. Mannich bases are very useful set of compounds having various applications in organic chemistry and pharmacy. This book will be useful to Chemistry and Pharmacy students studying this fascinating field of Computer aided drug designing and development.